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Regulation

10 min read

Homeostasis

Homeostasis is keeping the internal environment of the body constant, even when the outside conditions change. It includes body temperature (about 37 °C), blood sugar level, water content and pH. Homeostasis works by negative feedback: a change is detected, and the body acts to reverse it.

Negative feedbackA loop that keeps a body condition near a set point. A receptor detects a change, a control centre such as the brain compares it with the set point, and an effector acts to bring the condition back. When the condition returns to normal, the correcting action switches off. Body temperature, blood sugar and water balance are controlled this way.Set point (e.g. 37 °C)Receptor detects the changeControl centre (brain)Effector actsCondition returns to normaltoo hot or too cold?sweat or shiver

Temperature control

The brain contains a temperature centre that checks the blood. If the body is too hot, blood vessels in the skin widen (vasodilation) to lose heat, and sweat glands release sweat. If the body is too cold, the vessels narrow (vasoconstriction), sweating stops, hairs stand up and muscles shiver to make heat.

ConditionSkin blood vesselsSweatOther responses
Too hotWidenMoreHairs lie flat
Too coldNarrowNoneShivering, hairs stand up

Blood sugar

After a meal rich in carbohydrates the blood glucose rises. The pancreas releases the hormone insulin, which makes the liver and muscles take up glucose and store it as glycogen. When glucose falls, the hormone glucagon makes the liver release glucose. In diabetes the body does not make enough insulin, or does not respond to it.

In a healthy person insulin brings the glucose back to normal in about two hours. Without it the level stays high.
Try itBlood glucose after sugar

A healthy person releases insulin quickly, but a person with untreated diabetes does not. Choose the amount of sugar eaten.

Check yourself What is the main role of the hormone insulin?
Check yourself In the cold, the blood vessels in the skin...
Check yourself Negative feedback means...

Key terms

Homeostasis
Keeping the internal environment constant.
Negative feedback
A response that reverses a change.
Insulin
A hormone from the pancreas that lowers blood glucose.
Diabetes
A condition where blood glucose is not controlled.

Summary

  • Homeostasis keeps body conditions steady by negative feedback.
  • Skin blood vessels, sweating and shivering control body temperature.
  • Insulin lowers and glucagon raises blood glucose.
  • Diabetes is a failure of blood glucose control.